Pros
To succeed at Amazon, you really do need to drink the koolaid and subscribe to their peculiar ways. This is a place where you are given enormous latitude to chip in to solve problems. Your role is defined by what you want to drive and own, not by a title. I appreciate the autonomy that Amazon gives its leaders - for good and bad. We are given room to make mistakes, learn and grow from them. As a leader, I have made mistakes and I've been praised for my analysis of the failure and the corrective actions. I currently work in an organization with tenured Amazon leaders. They've collectively launched world-class operations and billion dollar businesses. It's amazing to learn from these leaders -- they are remarkably calm amid the chaos -- they've seen it all before.
Cons
You have to, as with any large organization, watch out for certain pockets where the work-life-balance is really screwy. The nice thing is there is very fluid lateral movement within the company. The policies have changed to make this easier and these poor leaders are being exposed quickly.