AstraZeneca Spain is a rising force in our global business. With headquarters in Madrid and our global hub in Barcelona, we’ve become an important international centre of excellence in the fight against critical disease. Boasting vibrant universities and business schools, the Barcelona ecosystem is a place where scientists can thrive. We attract a diverse workforce from across the globe, shining a beacon for innovation in a country that’s committed to clinical development.
We invite you to bring your talents to Barcelona where our respiratory medicine R&D and Global Marketing centre offers opportunities in R&D, IT, Commercial and HR. Or join us in Madrid and shape our growth in our BUs (Respiratory, Oncology & CVRM ), and a range of Corporate functions. Additionally, you can find sales roles throughout the country. Together, we’re contributing to a world-leading pipeline of therapeutics and delivering life-changing medicines to patients.
Calling all tech innovators, ownership takers, challenge seekers and proactive collaborators. At AstraZeneca Spain, breakthroughs born in the lab become transformative medicine for the world's most complex diseases. Alongside technical expertise, colleagues have the resilience, energy and collaborative mindset to change lanes, work with different teams and start projects from scratch.
Here, diverse minds and bold disruptors can meaningfully impact the future of healthcare using cutting-edge technology. Whether you join us in Madrid or Barcelona, you can make a tangible impact within a global biopharmaceutical company that invests in your future. Join a talented global team that's powering AstraZeneca to better serve patients every day.
Ready to make an impact in your career? If you're passionate, growth-orientated and a true team player, we'll help you succeed. Here are some of the skills and capabilities we look for.
This is a speak-up culture that values collaboration. You’ll proactively bring your unique perspectives, experiences and skills to the table and seek the same from others. With our international team composition and the need for fast-paced collaboration, you’ll always be building new connections with colleagues.
When you join us, you’ll be part of a team that embraces digital technology and data to transform the way we work and the work we do. Every day, you’ll help make history, empowered to ignite your creativity and build something enduring.
Here, the answers aren’t always available. So, you’ll need to bring a fearless, self-starter mindset to navigate uncharted territories. You’ll harness your ceaseless energy to discover and make the necessary connections with colleagues to shape the future and achieve maximum impact.
Seize ownership and excel with autonomy to enjoy the constant rush of ground-breaking discovery. Your ability to anticipate sudden shifts and adapt swiftly will prove critical as you make your mark in an environment that rewards initiative and resilience.
This role is based in Barcelona, with an on-site commitment of three days a week. Fluency in English is required.
Are you ready to put your medical oncology training to work at the heart of hemato-oncology development, where every decision you make strengthens patient safety and accelerates innovative trials? Do you thrive at the intersection of patient safety, trial strategy, and cross-functional leadership? In this role, you will be a key medical voice guiding global studies from early design through closeout, ensuring robust risk-benefit oversight and scientific rigor.
You will partner closely with Clinical Operations and cross-functional experts to shape protocols, engage investigators and external experts, and translate emerging data into decisive actions that keep studies on track and patients safe. You will also have the opportunity to lead process improvements and contribute to cross-asset, cross-indication initiatives—broadening your impact as our oncology portfolio advances across multiple indications and stages. Your work will directly influence how we identify patients earlier, execute trials faster, and bring transformative therapies to those who need them most.
Accountabilities:Responsible for ensuring the risk-benefit of a clinical study, maintaining the highest ethical and safety standards in compliance with FDA, EMEA, ICH, and GCP guidelines as well as AZ SOPs regarding safety.
Work cross-functionally in the design and implementation of clinical hemato-oncology projects as a member of the Clinical Sub-Team (CST), ensuring scientific and clinical rigor.
Contribute to the development of program strategy for assigned compounds/programs and collaborate with team members to develop compelling business cases for governance approval.
Provide clinical input to influence study design through collaboration with primary investigators, key external experts (KEE), study sites, team members, and internal stakeholders.
Participate or lead the review and assessment of new opportunities and ESRs as needed.
Support interactions with global medical affairs, marketing companies, and commercial teams to ensure cross-functional input into protocols.
Respond timely to investigational study sites for local ICF changes, protocol & EC/IRB questions/requests. Contribute to investigator and monitor training.
Support the development of clinical components of regulatory and EC/IRB submission documents for marketing approval.
Prepare clinical development plans integrating pre-clinical and early clinical findings while ensuring cross-functional alignment throughout early clinical development phases.
Present and defend protocols and clinical development plans at internal governance forums.
Serve as Medical Monitor, responsible for safety monitoring of clinical trials and as a medical expert for Phase I/II or Phase III studies.
Prepare various official and regulatory documents for agencies such as Dossiers, BLAs, INDs, Safety and Annual reports.
Implement clinical R&D policies, SOPs, and related directives.
Contribute to Department/Clinical initiatives to improve the quality and content of all clinical programs.
MD or international equivalent is required.
Medical oncology clinical training is required.
Clinical or research experience (in an academic, pharmaceutical or CRO environment) related to the design and/or conduct of clinical studies in oncology and/or malignant hematology is preferred.
Possesses general knowledge of Good Clinical Practice (GCP) and other regulations governing clinical research.
Possesses general knowledge of medical monitoring, regulatory approval processes in relevant countries, pharmaceutical industry/R&D operations, marketing, and commercial fundamentals.
Good understanding of clinical trials methodology.
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
Why AstraZeneca: Here, oncology leaders come together with data scientists, clinical operators, and external academic partners to turn bold ideas into studies that move fast and put patients first. With a broad, dynamic pipeline of novel molecules across multiple indications, you will influence programs at every stage—from shaping first-in-human protocols to driving pivotal trials—supported by strong investment, modern platforms, and a culture that values curiosity and kindness alongside ambitious goals. We bring uncommon combinations of experts into the same room to solve hard problems, learn quickly, and push for earlier detection and intervention, all with the shared aim of transforming outcomes and ultimately making cancer a less deadly disease.
Call to Action: Take the lead in advancing hemato-oncology—submit your application today and help turn rigorous science into life-changing medicines.
Date Posted
23-jun-2026Closing Date
13-jul-2026AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
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There are many things I enjoy when working at AstraZeneca, mainly the Speak up culture, the great colleagues that are in my teams, the great products that AstraZeneca provides to our patients and the challenging conversations I have around our medicines.
There are many things I enjoy when working at AstraZeneca, mainly the Speak up culture, the great colleagues that are in my teams, the great products that AstraZeneca provides to our patients and the challenging conversations I have around our medicines.
Working at AstraZeneca has impacted my life in such a positive way. I now have an improved work-life balance through creating my own schedule and time management, I feel a balance that I didn’t have before.
Working at AstraZeneca has impacted my life in such a positive way. I now have an improved work-life balance through creating my own schedule and time management, I feel a balance that I didn’t have before.
There are a lot of reasons why I enjoy working in AstraZeneca, my colleagues being one of them. My team members and the managers have provided a great deal of guidance in helping me to be more confident in my daily work.
There are a lot of reasons why I enjoy working in AstraZeneca, my colleagues being one of them. My team members and the managers have provided a great deal of guidance in helping me to be more confident in my daily work.
We're driven by our shared values of serving people, society and the planet. Our people make this possible, which is why we prioritise diversity, inclusivity, balance and sustainability. Discover what a career at AstraZeneca could mean for you.
We're passionate about being a great place to work, and 84% of our employees would recommend us as an employer. We've been recognised as a Top Employer in Spain, an EFR Family Responsible Business, and we achieved third place in Forbes Spain's Top 50 Best Places to Work list.
Diversity and inclusion are embedded in everything we do, and our different views, experiences and strengths enrich our culture. There's no salary gap at AstraZeneca, and the number of female employees has increased by four per cent over the last three years. We've also made all positions fully accessible.
Your wellbeing means a lot to us, and we're here to support you through all of life's ups and downs. That's why we offer an unpaid leave policy, annual leave, reduced-hours timetables and a host of benefits, including a retirement plan, long service award, and health and travel insurance.
We're committed to harnessing the power of science to become a more sustainable business. We've reduced our carbon footprint by over 9,000 kg of CO2 over the last two years, and we lead the European GoGreen Project, which aims to introduce environmentally friendly options in our fleet of corporate vehicles.
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